"Each year hundreds of new drugs are approved for the marketplace. The approval of a single new drug is the result of years of screening tens of thousands of compounds, performing pre-clinical research on their effects, and designing, implementing, and analyzing the results of clinical trials. This book provides a general guide to statistical methods used in the pharmaceutical industry, and is aimed at graduate students and researchers w ..."
"Thisisnowthefourtheditionof TheBasicsofS-Plus since1997.S-Plus saw a steady growth in popularity, and it established itself in many edu- tional and business places as a major data analysis tool.S-Plus is valued for its modern, interactive data analysis environment, whether it is the p- mary system or a complement to other standards like SAS (the latter is in particular true for the industry we work in, pharmaceuticals). We have followed ..."
"The LATEX Companion. Addison-Wesley, Reading, MA. Goossens, M. ...
Smoothing Techniques with Implementation in S. Springer-Verlag, New York.
Huet, S. ... Statistical Tools for Nonlinear Regression: A Practical Guide with S-
PLUS Examples. ... Computers and Typesetting, Vol. ... Scheffner, A., and
Krahnke, T., 1997."
"This book is devoted to the graphics of patient data: good graphs enabling straight-forward and intuitive interpretation, efficient creation, and straightforward interpretation. We focus on easy access to graphics of patient data: the intention is to show a large variety of graphs for different phases of drug development, together with a description of what the graph shows, what type of data it uses, and what options there are. The main ..."
"This is the idea behind the convex hull test. The number 12 was chosen
arbitrarily, as all that matters is the order induced on the sample space by the test
statistic. The three points marked 12 are the most extreme points, as they are the
directed extreme points of the sample space (Berger, 1998; Berger et al., 1998).
Once these three p=0.0116 size= 0.0411 10- o o o 3 4 5 6 7 8 9 10 11 12 10- o 1
2 3 4 5 6 7 8 9 to 11 12 9-i o o o ..."
"Andreas Krause, Melvin Olson. Johnson ... A, The TEXbook, 11th ed. ... Statistical
Software Newsletter in Computational Statistics and Data Analysis, 19, 5: 595-
604, (http://www.genedata.com/ andreas/internet/internet.html) Lamport, L., 1985."
"The example patient's observed scores at each time point are indicated by Xs in
the slide and the mean of the placebo distribution is indicated by Ps. As the slide
builds, each value drawn from the placebo distribution (shown schematically at
the right side as a bell curve) appears for each imputation. The bell curve shows
the distribution from which these values were drawn. A similar scenario follows in
red for imputed values draw ..."
"Note There are very few strange cases where S-Plus refuses to import or export
ASCII data with the expected format. In such cases, you have to give up the
convenience of the import/export facilities presented here and use the “basic”
method ..."
Fashion in Steel(Illustrated) The Landsknecht Armour of Wilhelm von Rogendorf by Stefan Krause, Sabine Haag, Andreas Zajic Hardcover, 128 Pages, Published 2017 by Other Distribution ISBN-13: 978-0-300-23086-4, ISBN: 0-300-23086-9
The Basics of S-PLUS(3rd Edition) (Statistics and Computing) by AndreasKrause, Melvin Olson Paperback, 419 Pages, Published 2002 by Springer ISBN-13: 978-0-387-95456-1, ISBN: 0-387-95456-2
"This book explains the basics of S-PLUS in a clear style at a level suitable for people with little computing or statistical knowledge. Unlike the S-PLUS manuals, it is not comprehensive, but instead introduces the most important ideas of S-PLUS through the use of many examples. Each chapter also includes a collection of exercises that are accompanied by fully worked-out solutions and detailed comments. The volume is rounded off with pr ..."
"Each year hundreds of new drugs are approved for the marketplace. The approval of a single new drug is the result of years of screening tens of thousands of compounds, performing pre-clinical research on their effects, and designing, implementing, and analyzing the results of clinical trials. This book provides a general guide to statistical methods used in the pharmaceutical industry, and is aimed at graduate students and researchers w ..."
"S-PLUS is a powerful tool for interactive data analysis, creating graphs, and implementing customized routines. Originating as the S language of AT&T Bell Laboratories, its modern language and flexibility make it appealing to data analysts from many scientific fields. This book explains the basics of S-PLUS in a clear style at a level suitable for people with little computing or statistical knowledge. Unlike the S-PLUS manuals, it is no ..."